This gene encodes a dual-specificity phosphatase that acts on both phosphotyrosine and phosphoserine.
It is required for muscle cell differentiation and mutations in this gene have been identified as being responsible for X-linked myotubular myopathy.
Applications:Suitable for use in ELISA and Western Blot.
Other applications have not been tested.
Recommended Dilutions: Peptide ELISA Titer: 1:16,000Western Blot: ~70kD band observed in lysates of Human Muscle and of cell line HepG2 (calculated MW of 69.9kD according to NP_000243.1).
In transfected HEK293 transiently expressing MTM1 a band of approx.
65kD is observed.
This band is not observed in the non-transfectedOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by peptide affinity chromatography.
Form：Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes human MTM1. Species sequence homology: bovine
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to C-SSPSQMMPHVQTHF, from the C Terminus of human MTM1 (NP_000243.1).
