The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization.
Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone.
Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty.
Three transcript variants encoding two different isoforms have been found for this gene.
Applications:Suitable for use in ELISA.
Other applications have not been tested.
Recommended Dilutions: Peptide ELISA Titer: 1:16,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by peptide affinity chromatography.
Form:Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity:Recognizes IGFALS. Species sequence homology: human, mouse, rat, canine, bovine, porcine.
Isotype:IgG
Calc Applications Abbrev:E
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to C-GLDLRDLSEAH, from the C-Terminus of human IGFALS (NP_004961.1).