ZWINT is clearly involved in kinetochore function although an exact role is not known.
It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores.
The protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase.
It has a uniform distribution in the cytoplasm of interphase cells.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:1,000Indirect Flow Cytometry: 1:10-1:50Immunohistochemistry: 1:50-1:100Western Blot: 1:50-1:100Optimal dilutions to be determined by the researcher
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Purified
Purity：Purified by ammonium sulfate precipitation.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human ZWINT. Species Crossreactivity: mouse.
Isotype：IgG
Calc Applications Abbrev：E FC IHC WB
Calc Crossreactivity：Hu Mo
Immunogen：KLH-conjugated synthetic peptide between amino acids 66-96 in the center region of human ZWINT
