PLAU, a member of the peptidase family S1, is a potent plasminogen activator and is clinically used for therapy of thrombolytic disorders.
PLAU specifically cleaves the Arg-|-Val bond in plasminogen to form plasmin.
The protein is found in high and low molecular mass forms.
Each consists of two chains, A and B.
The high molecular mass form contains a long chain A.
Cleavage occurs after residue 155 in the low molecular mass form to yield a short A1 chain.
The protein is used in Pulmonary Embolism (PE) to initiate fibrinolysis.
Structurally, PLAU contains 1 EGF-like domain and 1 kringle domain.
Applications:Suitable for use in ELISA, Western Blot, Immunofluorescence, Indirect Flow Cytometry and Immunohistochemistry.
Other applications have not been tested.
Recommended Dilution:Western Blot: 1:1000Immunofluorescence: 1:10-1:50Indirect Flow Cytometry: 1:10-1:50Immunohistochemistry: 1:10-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Purified
Purity：Purified by ammonium sulfate precipitation.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human PLAU.
Isotype：IgG
Calc Applications Abbrev：E FC IF IHC WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 396-426 in the C-terminal region of human PLAU.
