84-1160-90 TGFBR1, ID (TGF-beta Receptor Type I, TGFR-1, Transforming Growth Factor-beta Receptor Type I, TGF-beta Type I Receptor, TbetaR-I, TGF-beta Type I Receptor, Serine/Threonine-protein Kinase Receptor R4, SKR4, Activin Receptor-like Kinase 5, ALK-5, TGF beta Receptor I) 200ul T8250-31A
84-1160-90 TGFBR1, ID (TGF-beta Receptor Type I, TGFR-1, Transforming Growth Factor-beta Receptor Type I, TGF-beta Type I Receptor, TbetaR-I, TGF-beta Type I Receptor, Serine/Threonine-protein Kinase Receptor R4, SKR4, Activin Receptor-like Kinase 5, ALK-5, TGF beta Receptor I) 200ul T8250-31A
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm.
The encoded protein is a serine/threonine protein kinase.
Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:1000Immunohistochemistry (FFPE): 1:50-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Purified
Purity:Purified by ammonium sulfate precipitation
Form:Supplied as a liquid in PBS, 0.09% sodium azide
Specificity:Recognizes human TGFBR1
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 134-163 in the central region of human TGFBR1. Species Sequence Homology: bovine, porcine, rat and mouse