PIM1, which belongs to the Serine/Threonine protein kinase family, is thought to play a role in signal transduction in blood cells.
The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer.
It may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3.
PIM1 is expressed primarily in cells of the hematopoietic and germ line lineages.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000Immunohistochemistry (FFPE): 1:50-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Purified
Purity:Purified by ammonium sulfate precipitation.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human Pim1.
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 374-404 in the C-terminal region of human Pim1, UniProt Accession #P11309. Species sequence homology: bovine