PIGR binds polymeric IgA and IgM at the basolateral surface of epithelial cells.
The complex is then transported across the cell to be secreted at the apical surface.
During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
Applications:Suitable for use in ELISA, Western Blot, Immunofluorescence, Immunohistochemistry and Indirect Flow Cytometry.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:1000Immunofluorescence: 1:10-1:50Immunohistochemistry (FFPE): 1;10-1;50Indirect Flow Cytometry: 1:10-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography
Form：Supplied as a liquid in PBS, 0.09% sodium azide
Specificity：Recognizes human PIGR
Isotype：IgG
Calc Applications Abbrev：E FC IF IHC WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 646-672 in the C-terminal region of human PIGR
