NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily.
Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts.
The encoded protein acts as a nuclear transcription factor.
Translocation of the protein from the nucleus to mitochondria induces apoptosis.
Applications:Suitable for use in ELISA and Dot Blot.
Other applications not tested.
Recommended Dilution:Dot Blot: 1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human NR4A1 when phosphorylated at Ser351.
Isotype:IgG
Calc Applications Abbrev:DB E
Calc Crossreactivity:Hu
Immunogen:KLH-conjugated synthetic phosphopeptide mapping to a fragment of amino acid residues surrounding S351 of human NR4A1, UniProt Accession #P22736. Species sequence homology: mouse, rat