Mos, the c-mos protooncogene product, is a key regulator of meiosis in vertebrates.
MOS is a 39kDa proto oncogene (c-Mos) encoded protein serine/threonine kinase.
MOS is a monomeric protein that indirectly activates MAP kinase (Erk1/2) by directly phosphorylating MAP kinase kinase (Mck, MAPKK, MKK).
MOS is known as a cytostatic factor (CSF) and is also thought to arrest unfertilized amphibian and mammalian cells during M phase, thus regulating oocyte maturation.
MOS is destroyed before fertilisation, after exit from meiosis II, making it a good marker for studies of eggs during oogenesis and maturation.
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1,000Immunohistochemistry: 1:10-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Purified
Purity：Purified by ammonium sulfate precipitation.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human MOS.
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide selected from the C-terminal region of human MOS (KLH).
