MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family.
This kinase is known to play a critical role in mitogen growth factor signal transduction.
It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3.
The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases.
The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.
Applications:Suitable for use in Dot Blot.
Other applications not tested.
Recommended Dilution:Dot Blot: 1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human MEK2 when phosphorylated at Ser226.
Isotype：IgG
Calc Applications Abbrev：DB
Calc Crossreactivity：Hu
Immunogen：Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser226 of human MEK2 conjugated to KLH. Species Sequence Homology: chicken, Drosophila, C.Elegans, Hamster, Mouse, Rat, Xenopus.
