IGFBP4 has an IGFBP domain and a thyroglobulin type-I domain.
The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms.
Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
Applications:Suitable for use in ELISA, Western Blot and Indirect Flow Cytometry.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:2000Indirect Flow Cytometry: 1;25Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human IGFBP4. Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:E FC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 66-92 in the N-terminal region of human IGFBP4. Species Sequence Homology: bovine and porcine