84-1150-81 GIT1, phosphorylated (Tyr554) (ARF GTPase-activating protein GIT1, G protein-coupled receptor kinase-interactor 1, GRK-interacting protein 1, Cool-associated and tyrosine-phosphorylated protein 1, Cat-1, GIT1) 200ul G2035-07P
84-1150-81 GIT1, phosphorylated (Tyr554) (ARF GTPase-activating protein GIT1, G protein-coupled receptor kinase-interactor 1, GRK-interacting protein 1, Cool-associated and tyrosine-phosphorylated protein 1, Cat-1, GIT1) 200ul G2035-07P
GIT1 is a GTPase-activating protein for the ADP ribosylation factor family.
It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization, increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.
It sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes.
Applications:Suitable for use in ELISA and Dot Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000 Dot Blot: 1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human GIT1 when phosphorylated for Tyr554.
Isotype：IgG
Calc Applications Abbrev：DB E
Calc Crossreactivity：Hu
Immunogen：Synthetic phosphopeptide corresponding to a portion of amino acids within aa540-569 surrounding Tyr554 of human GIT1, conjugated to KLH (Q9Y2X7).
