84-1145-73　Aurora C, NT (M1) (Aurora/IPL1/Eg2 Protein 2, Aurora/IPL1-related Kinase 3, Serine/Threonine Protein Kinase 13, Aurora-related Kinase 3, ARK-3, Aurora Kinase C, Serine/Threonine-protein Kinase Aurora-C, AURKC, AIE2, AIK3, ARK3, STK13) 200ul　A4190-17F

特徴

• Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases.
• The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation.
• Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis.
• This protein is localized to centrosome from anaphase to cytokinesis.
• Expression is limited to testis in normal cells.
• Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells.
• Aurora-C expression is maximum at M phase.
• Applications:Suitable for use in ELISA, Immunofluorescence, Immunohistochemistry and Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:1000immunohistochemistry (FFPE): 1:100Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.