84-1144-94 AMPK1 (Ser487) (5'-AMP-activated Protein Kinase, Catalytic Subunit alpha-1 Chain, AMPK Subunit alpha-1, PRKAA1) 200ul A1475-01Q1
特徴
- PRKAA1 belongs to the ser/thr protein kinase family.
- It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK).
- AMPK is a cellular energy sensor conserved in all eukaryotic cells.
- The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio.
- AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation.
- It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.
- Applications:Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:ELISA: 1:1,000Western Blot: 1:50-1:100Immunohistochemistry: 1:10-1:50Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for at least 12 months.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:200ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, 0.09% sodium azide.
- Specificity:Recognizes human PRKAA1.
- Isotype:IgG
- Calc Applications Abbrev:IHC WB
- Calc Crossreactivity:Hu
- Immunogen:Synthetic non-phosphoeptide corresponding to amino acid residues surrounding Ser487 of human PRKAA1 (KLH).
- Shelf Life:1year
- Swiss Prot Number:Q86VS1
- EU Commodity Code:30021010
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