RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport.
Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways.
RAB7 is a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes.
This protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori.
Applications:Suitable for use in Indirect Flow Cytometry, Immunohistochemistry, ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:2000Immunohistochemistry (FFPE): 1:25Indirect Flow Cytometry: 1:25Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human RAB7. Species Crossreactivity: mouse, rat
Isotype：IgG
Calc Applications Abbrev：E FC IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 176-204 in the C-terminal region of human RAB7, UniProt Accession #P51149.
