SHIP1, SH2-containing inositol phosphatase 1, hydrolyzes phosphatidylinositol-3,4,5-triphosphate to phosphatidylinositol-3,4-bisphosphate.
SHIP1 is a cytosolic phosphatase that affects calcium flux, cell survival, growth, cell cycle arrest, and apoptosis mediated through the PI3K and Akt pathways.
SHIP1 is a negative regulator B lymphoid cell, myeloid cell, and mast cell activation.
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1,000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Purified
Purity:Purified by ammonium sulfate precipitation.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human SHIP1.
Isotype:IgG
Calc Applications Abbrev:E IHC
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide selected from the C-terminal region of human SHIP1 (KLH).