This gene encodes a member of the Ser/Thr protein kinase family.
This kinase is regulated through direct phosphorylation by p38 MAP kinase.
In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation.
Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo.
Two transcript variants encoding two different isoforms have been found for this gene.
Applications:Suitable for use in ELISA, Dot Blot, and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Immunohistochemistry (FFPE): 1:50-1:100Dot Blot: 1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human MAPKAPK2 when phosphorylated at Ser272.
Isotype：IgG
Calc Applications Abbrev：DB E IHC
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues surrounding Ser272 of human MAPKAPK2. UniProt Accession #P49137. Species Sequence Homology: mouse and rabbit
