This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases.
This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway.
The activity of this protein has been implicated in controlling cell growth and differentiation.
Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Transcript Variant: This variant (1) represents the longer transcript but encodes the shorter isoform (a).
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1,000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human RSK1 when phosphorylated at Ser364.
Isotype:IgG
Calc Applications Abbrev:E IHC
Calc Crossreactivity:Hu
Immunogen:Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser364 of human RSK1 (KLH).