84-1141-01　FADD, phosphorylated (Ser191) (FADD Protein, FAS-associating Death Domain-containing Protein, FAS-associated Death Domain Protein, Mediator of rEceptor Induced Toxicity, Fadd, Mort1) 200ul　F0019-53R

特徴

• FADD is an apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors.
• The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation.
• Active caspase-8 initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
• Applications:Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:1,000Western Blot: 1:100-1:500Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.