The Dcr-1 gene encodes a bidentate ribonuclease that is homologous to E.
coli RNAse III.
Dcr-1 is required both for RNA interference and for synthesis of small developmental RNAs.
Dcr-1 interacts in vivo with RDE-4, a double-stranded RNA (dsRNA) binding protein required for RNAi that interacts with trigger dsRNAs and may function to deliver dsRNAs to Dcr-1 for endonucleolytic processing.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:c.elegans
Grade:Purified
Purity:Purified by ammonium sulfate precipitation.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes C. elegans Dcr-1.
Isotype:IgG
Calc Applications Abbrev:E
Calc Crossreactivity:Ce
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1068-1097 of C. elegans Dcr-1.