84-1135-26 Kremen, NT (Kremen protein 1, Kringle-containing Protein Marking The Eye And The Nose, Kringle Domain-containing Transmembrane Protein 1, Dickkopf Receptor, KREMEN1, KRM1) 200ul K5000-01
84-1135-26 Kremen, NT (Kremen protein 1, Kringle-containing Protein Marking The Eye And The Nose, Kringle Domain-containing Transmembrane Protein 1, Dickkopf Receptor, KREMEN1, KRM1) 200ul K5000-01
Kremen is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling.
The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6).
It contains extracellular kringle, WSC, and CUB domains.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:1000Immunohistochemistry (FFPE): 1:50-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Purified
Purity:Purified by ammonium sulfate precipitation.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human Kremen.
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 6-37 in the N-terminal region of human Kremen, UniProt Accession #Q96MU8.