84-1133-97 Bad, ID (Bcl2 Antagonist Of Cell Death, BAD, Bcl-2-binding Component 6, Bcl-XL/Bcl-2-Associated Death Promoter, Bcl-2-like 8 Protein, BAD, BBC6, BCL2L8) 200ul B0003-47H1
特徴
- Bad is a member of the BCL-2 family.
- BCL-2 family members are known to be regulators of programmed cell death.
- This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity.
- Proapoptotic activity of this protein is regulated through its phosphorylation.
- Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein.
- Applications:Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:ELISA: 1:1,000Western Blot: 1:100-1:500Immunohistochemistry: 1:10-1:50Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for at least 12 months.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:200ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, 0.09% sodium azide.
- Specificity:Recognizes human Bad.
- Isotype:IgG
- Calc Applications Abbrev:E IHC WB
- Calc Crossreactivity:Hu
- Immunogen:Synthetic peptide selected from the center region of human Bad (KLH).
- Shelf Life:1year
- Swiss Prot Number:Q92934
- EU Commodity Code:30021010
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