This gene belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans.
It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function.
The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake.
Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa.
In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Frozen, Paraffin): 1:1000-1:2000 using FITC.
Incubate overnight at 4ºC
Optimal dilutions to be determined by the researcher.
Positive Control:Formalin-fixed paraffin sections of pig duodenal pancreas.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：50ul
Host：rabbit
Source Antibody：bovine
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder. Reconstitute in 50-100ul sterile ddH2O. Dilute further in 0.1M PBS, 1% BSA, 0.09% sodium azide.
Specificity：Recognizes bovine Pancreatic Polypeptide. Species Crossreactivity: Human and porcine
