Interleukin 6 (IL-6) is a pluripotent 20-22kD cytokine which plays a role in the pathophysiology of severe infection and regulates the immune response, acute phase reaction and hematopoiesis.
IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma.
Continuous IL-6 gene expression makes an essential contribution to a multistep oncogenesis of plasma cell neoplasia.
IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas.
Applications:Suitable for use in ELISA, Western Blot and Neutralization.
Other applications not tested.
Recommended Dilution:Western Blot: 1:10Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:1ml
Host:rabbit
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
Specificity:Recognizes natural and recombinant mouse IL-6. Inhibits the biological activity of natural and recombinant mouse IL-6 as determined with the B9 cell bio-assay. Species Crossreactivity: Rat