84-1131-97　［取扱停止］Complement C1q (Complement Component 1, q Subcomponent) (FITC) 1ml　C0010-02K

特徴

• Human complement component 1, q subcomponent (C1q) is a 156kD secreted protein.
• C1q associates with proenzymes C1r and C1s to form the calcium-dependent C1 complex, the first component of the serum complement system.
• C1q is composed of six A, six B-chains and six C-polypeptide chains.
• Each chain contains a collagen-like region located near the N-terminus and a C-terminal globular region.
• These regions bind the Fc region of IgM and IgG molecules, initiating the classical pathway of complement activation.
• C1q deficiency has been associated with lupus erythematosus and glomerulonephritis.
• Applications:Suitable for use in Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry (Frozen): 1:25-1:50 using the Direct Method
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: FITC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.