Aldolase (fructose bisphosphate aldolase), a glycolytic enzyme, catalyzes the conversion of fructose 1, 6-bisphosphate to 3-phosphoglyceraldehyde.
This ubiquitous enzyme is present as three different isozymes: aldolase A, aldolase B and aldolase C.
Studies suggest the potential diagnostic value of quantitive anlysis of aldolase A for hepatocarcinoma (1).
Furthermore, the change of aldolase B gene expression levels has also been observed in certain patients with this primary tumor (2,3).
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography.
Form:Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol.
Specificity:Recognizes endogenous levels of total human fructose bisphosphate aldolase A protein. May detect total fructose bisphosphate aldolase B and fructose bisphosphate aldolase C proteins. Species crossreactivity: Mouse, rat, hamster and monkey
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hm Hu Mk Mo
Immunogen:Synthetic peptide corresponding to the sequence of human fructose bisphosphate aldolase.