84-1131-34　Orexin A (Orexin-A, Hypocretin (Orexin) Neuropeptide Precursor, Hypocretin 1, Hypocretin-1, HCRT1, Hypocretin A, Hypocretin, HCRT, Orexin, OX, PPORX, PPOX) 100ul　O7500-06B

特徴

• Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions.
• A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested.
• Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.
• SUBCELLULAR LOCATION: Endoplasmic reticulum; rough endoplasmic reticulum.
• Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses.
• SIMILARITY: Belongs to the orexin family.
• Applications: Suitable for use in Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry: 1-1000-1:2000Optimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months at -20°C.
• Reconstitute with sterile ddH2O or PBS.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.