The matrix metalloproteinases (MMPs) are a large family of zinc endopeptidases.
All MMPs are synthesized as inactive proenzymes.
The activation of these proenzymes is a critical step that leads to degradation of extracellular matrix components such as fibronectin and collagen type III.
MMP8 is known to degrade fibrillar type I, II, and III collagens.
Applications: Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 0.75ug/mlImmunohistochemistry (FFPE): 1-2ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS, 0.05% thimerosal, 5% BSA, 0.05% sodium azide. Reconstitute with 100ul of sterile ddH2O.
Specificity：Recognizes human Matrix metalloproteinase-8 at 53kD. Species Crossreactivity: rat. Species sequence homology: mouse
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Rt
Immunogen：Synthetic peptide corresponding to aa103-115, PGNPKWERTNLTY of human Matrix metalloproteinase-8. Coupled to BSA.
