C-C Chemokine Receptor type 5 (CCR5) is a G-protein coupled receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES.
CCR5 and its ligands may also play important roles in the control of granulocytic lineage proliferation or differentiation as well as pathogenesis of viruses such as HIV.
Applications: Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 0.1-0.5ug/mlImmunohistochemistry: 0.5-1ug/ml for formalin fixed paraffin tissues.
Heat mediated antigen retrieval is recommended
Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% Thimerosal, 0.05% sodium azide. Reconstitute with 100ul sterile ddH2O.
Specificity：Recognizes human CCR5 at ~41kD.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa19-34, PCQKINVKQIAARLLP from the N-terminal of human CCR5 conjugated to BSA.Species sequence homology: rat and mouse
