Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (Hsp10s).
Cpn10 acts as a co-chaperone and interacts with the Hsp60 family to promote proper folding of polypeptides.
Cpn10 and Cpn60 both exhibit sevenfold axis of symmetry and function as a team in the protein folding and assembly process (1).
Cpn10 has been located in human platelets, but is also present in human maternal serum (2, 3).
It has been reported that human Cpn10 is identical with early pregnancy factor, which is involved in control over cell growth and development.
This identification suggest that Cpn10 may act like a hormone in stressful situations such as pregnancy (4).
Applications:Suitable for use in ELISA, Western Blot, Immunoprecipitation and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot:1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS with 0.02% sodium azide, pH7.3.
Specificity：Recognizes human HSPE1. Species Crossreactivity: mouse, rat, bovine, canine, guinea pig, porcine, sheep, xenopus.
