IP3 Receptor 1 is an intracellular channel that when stimulated by inositol 1,4,5-triphosphate mediates the release of calcium from the endoplasmic reticulum.
Defects within the gene ITPR1 cause a group of cerebellar disorders known as spinocerebellar ataxia type 15 (SCA15).
This receptor is widely expressed in tissue.
Applications:Suitable for use in Western Blot and Immunohistochemisty.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500Immunohistochemistry (Paraffin): 1:100Optimal dilutions to be determined by the researcher.
Positive Control:C2C12 cell lysates
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as a liquid.
Specificity：Recognizes human IP3 Receptor 1 at ~300kD. Species Crossreactivity: mouse.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to the N-terminal of human IP3 Receptor 1. Species Sequence Homology: canine and rat.
