Synphilin-1 is a cytoplasmic protein which associates with alpha-synuclein in vivo.
Alpha-Synuclein is a major component of lewy bodies in patients with sporadic Parkinson's disease (PD) and mutations of alpha-synuclein are involved in familial forms of PD.
Reports suggest that synphilin-1 may play a role in lewy body formation in association with alpha synuclein.
Applications:Suitable for use in Immunofluorescence, ELISA, Immunohistochemistry and Western Blot.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:400ELISA: 1:5,000-1:10,000Western Blot: 1:2,000Optimal dilutions to be determined by the researcher.
Positive Control Tissue:Human Brain
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：goat
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as liquid in 0.09% sodium azide.
Specificity：Recognizes human Synphilin 1.
Isotype：IgG
Calc Applications Abbrev：E IF IHC WB
Calc Crossreactivity：Hu
Immunogen：Peptide, SLELNGEKDKDKGRTLQRT, corresponding to residues 829-847 of human synphilin 1.
