84-1129-36 [取扱停止]Solute Carrier Family 7, NT (Cationic Amino Acid Transporter, Y+ System), Member 11 (Solute Carrier Family 7 Member 11, SLC7A11, Amino Acid Transport System xc xCT, Calcium Channel Blocker Resistance Protein CCBR1, Cystine/glutamate Transporter, xCT) 50ug S5329-08G
84-1129-36 [取扱停止]Solute Carrier Family 7, NT (Cationic Amino Acid Transporter, Y+ System), Member 11 (Solute Carrier Family 7 Member 11, SLC7A11, Amino Acid Transport System xc xCT, Calcium Channel Blocker Resistance Protein CCBR1, Cystine/glutamate Transporter, xCT) 50ug S5329-08G
This heterodimer forms a Na+ independent amino acid transport system which leads to the uptake of extracellular L-cystine in conjunction to L-glutamate efflux.
This system is thought to play an important role in the protection of neurons and activated macrophages against oxidative stress.
Solute Carrier Family 7 is the receptor which mediates Kaposi's sarcoma herpesvirus (KSHV) cell fusion.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 20-30ug/mlRequires antigen retrieval using heat treatment for 20 minutes prior to staining of paraffin sections.
Optimal dilutions to be determined by the researcher.
Positive Control Tissue:Neurons or astrocytes
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes an epitope within the N-terminal of the cysteine/glutamate transporter SLC7A11.
Isotype:IgG
Calc Applications Abbrev:IHC
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to the N-terminal region of human SLC7A11.