Ras homologue enriched in brain (Rheb) is a 17kD G-protein and evolutionarily conserved Ras family member, widely expressed in tissues other than the brain.
Compared with many small GTPases, Rheb is unique since it exists in a highly activated state in mammalian cells.
Rheb also plays an important part in regulating the TOR signally pathway.
Although Rheb is expressed at relatively high levels in the adult cortex, it can be rapidly induced in brain neurons by synaptic activity.
Following a seizure, it is transiently induced in the hippocampus.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1-2ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity：Recognizes human Rheb. Species Crossreactivity: rat, mouse
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to 15aa at the internal region of human Rheb.
