Indoleamine 2,3-dioxygenase (IDO) is an enzyme that is responsible for converting tryptophan to kynurenines.
IDO is expressed by a wide variety of tissues and IDO can be upregulated by interferon gamma.
IDO modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response.
Reports suggest that IDO is involved in the suppression of the immune response to tumors and blocking the IDO pathway may be a potential target for immunotherapy.
Applications:Suitable for use in Immunohistochemistry and Western Blot.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): Requires antigen retrieval using heat treatment prior to staining of paraffin sections
Western Blot: 1:1,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：sheep
Source Antibody：human
Grade：Purified
Purity：Purified by ammonium sulfate precipitation.
Form：Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
Specificity：Recognizes human indoleamine 2,3-dioxygenase. Species Crossreactivity: marmoset, rhesus monkey
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mk
Immunogen：Recombinant protein corresponding to human indoleamine 2,3-dioxygenase.
