Immunoglobulins are composed of two identical heavy chains and two identical light chains; disulfide-linked (PubMed:20176268).
An IgD molecule contains thus a delta heavy chain combined with either a kappa or a lambda light chains.
Kappa light chains are found predominantly on the membrane IgD (mIgD) form and lambda on the secreted IgD (sIgD) form, this fact is poorly understood.
Membrane-bound IgD molecules are non-covalently associated with a heterodimer of CD79A and CD79B (PubMed:11282392).
Applications:Suitable for use in Flow Cytometry.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: PE conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
仕様
Size:500ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).
Specificity:Recognizes human IgD and has been cross-adsorbed against human IgA, IgG and IgM to ensure class specificity. May also react with mouse IgD.