HIV is a member of the genus Lentivirus, part of the family of Retroviridae, which use reverse transcriptase to convert the viral RNA genome into double stranded DNA.
This is then integrated into the cell’s DNA, which is followed by latency or active HIV replication.
HIV primarily infects CD4+ T lymphocytes, resulting in their dramatic decline.
When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections.
If untreated, this can lead to AIDS (Acquired Immunodeficiency Syndrome).
Applications:Suitable for use in ELISA, Immunohistochemistry and Western Blot.
Other applications not tested.
Recommended Dilutions:Immunohistochemistry: Frozen sectionsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：1ml
Host：goat
Grade：Purified
Purity：Purified.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Recognizes gp120, an exterior envelope glycoprotein on the surface of the virus particle that acts as a receptor for CD4 and chemokine receptors on macrophages and T-lymphocytes. It does not react with human T cells, B cells, normal bovine serum or normal human serum.
