Haptoglobin, also known as Hp, is an acute phase plasma glycoprotein synthesized by the liver in response to infection or inflammation.
Haptoglobin binds hemoglobin released by erythrocytes with high affinity, and functions to block the oxidative activity of hemoglobin and prevent renal damage.
The haptoglobin-hemoglobin complex is rapidly removed from the circulation by monocytes and macrophages, via the receptor CD163.
The haptoglobin genotype has been demonstrated to be an independent risk factor for cardiovascular disease in multiple epidemiological studies.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：1ml
Host：sheep
Source Antibody：human
Grade：Purified
Purity：Purified
Form：Supplied as a liquid in PBS, 0.01% thiomersal. Labeled with horseradish peroxidase (HRP).
Specificity：Recognizes human Haptoglobin (HRP).
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Hu
Immunogen：Native, purified human haptoglobin from serum.
