Aminopeptidase P1 (APP1), also known as XPNPEP1 (X-prolyl aminopeptidase), is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue.
Deficiency of X-prolyl aminopeptidase results in excretion of large amounts of imino-oligopeptides in urine.
The sequence of human APP1 is 99%, 97%, and 95% identical to that of canine, bovine, and mouse/rat.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:32000Western Blot: 0.3-1ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, pH7.3, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes human XPNPEP1. Sequence Homology: mouse, rat, bovine, porcine, canine.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to C-LIRETQPISKQH, from the C-Terminus of human XPNPEP1 (NP_065116.2; NP_001161076.1).
