TREML1 is a type I transmembrane protein that differs from TREM in the cytoplasmic region by having two ITIMs (Immunoreceptor Tyrosine-based Inhibition Motif).
A splice variant lacking ITIMs in its cytoplasmic domain also exists.
TREML1 is found only in platelets and megakaryocytes.
The extracellular region of human and mouse TLT-1 share 75% amino acid sequence identity.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:2000Western Blot: 0.3-1ug/ml detects ~30kDa band observed in Human Bone Marrow lysates (calculated MW of 32.7kDa according to NP_835468.1)
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, pH7.3, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes human TREML1.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to CGPAQNPPNNQTPS, from the C-Terminus of thuman TREML1 (NP_835468.1).
