STAG3 is a meiosis specific component of cohesin complex.
The cohesin complex is required for the cohesion of sister chromatids after DNA replication.
The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped.
At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Titer:ELISA (Peptide): 1:32,000
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes STAG3.
Isotype：IgG
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to C-KHYNKFYEDYGD, from the internal region of STAG3 (NP_058660.2). Species sequence homology: mouse, human, rat
