Roundabout Homolog 1 (ROBO1) is a type I transmembrane protein belonging to the ROBO family, which defines a novel subfamily of immunoglobulin superfamily proteins.
ROBO family proteins are evolutionarily conserved receptors that interact with the secreted Slit proteins.
ROBO-Slit interactions play an important role in axon guidance across the midline during central nervous system development.
ROBO signaling also has a role in tumor angiogenesis and immune responses.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:ELISA: 1:128,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Specificity:Recognizes ROBO1/DUTT1. Sequence homology: mouse, rat, canine.
Isotype:IgG
Calc Crossreactivity:Mo
Immunogen:Synthetic peptide corresponding to C-QKARPAKKQKHQ, from the internal region of ROBO1/DUTT1 (NP_062286.2).