CD11a (also known as integrin alphaL or lymphocyte function-associated antigen (LFA)-1 alpha chain) complex with the Beta2 subunit of the integrin family, CD18, to form the cell surface heterdimer, LFA-1 or CD11a /C18 (alphaLBeta2).
LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes.
It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses.
MAb DF1524 reacted with CD11a transfected cells and potently blocked LFA-1 dependent homotypic cell aggregation.
Applications:Suitable for use in Peptide ELISA, Western Blot and Immunohistochemistry.
Steamed antigen retrieval with citrate buffer pH 6 is recommended
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography
Form：Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Specificity：Recognizes human CD11A/ Integrin Alpha L.
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to C-YQVRIQPSIHDHN, from the internal region of human CD11A/ Integrin Alpha L (NP_002200.2; NP_001107852.1). Species Sequence Homology: canine
