Urodilatin is a natriuretic peptide isolated from human urine and belongs to the family of A type natriuretic peptides.
Urodilatin is differentially processed to a peptide of 32aa from the same precursor as ANP.
It is synthesized in kidney tubular cells and secreted luminally.
After secretion from epithelial cells of the distal and/or connecting tubules, Urodilatin interacts downstream at distal segments of the nephron with luminally located receptors whereby it regulates Na(+) and water reabsorption.
Thus, the physiological function of the renal Urodilatin system can be described as a paracrine intrarenal regulator for Na(+) and water homeostasis, considering Urodilatin as a real diuretic natriuretic regulatory peptide.
Applications:Suitable for use in RIA.
Other applications not tested.
Recommended Dilutions:RIA: 1:240,000Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：20ul
Host：sheep
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with sterile ddH2O.
Specificity：Recognizes human Urodilatin. No crossreactivity with human ANP aa1-28, <0.1%; human pro-ANP aa1-30, human pro-ANP aa31-67, human pro-ANP aa79-98, human pro-ANP aa1-98 <0.1%, human BNP <0.1%.
Isotype：IgG
Calc Applications Abbrev：RIA
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa95-101, TAPRSLR-ßAC from human Urodilatin comjugated to KLH
