Human Prolactin (lactogenic hormone) is secreted from the anterior pituitary gland in both men and women.
Human Prolactin is a single chain polypeptide hormone with a molecular weight of approximately 23,000.
The release and synthesis of Prolactin is under neuroendocrinal control, primarily through Prolactin Releasing Hormone and Prolactin Inhibiting Hormone.
Women normally have slightly higher basal Prolactin levels than men.
Apparently, there is an estrogen-related rise at puberty and a corresponding decrease at menopause.
The primary functions of Prolactin are to initiate breast development and to maintain lactation.
Prolactin also suppresses gonadal function.
During pregnancy, Prolactin levels increase progressively to between 10 and 20 times normal values, declining to non-pregnant levels by 3-4 weeks post-partum.
Breastfeeding mothers maintain high levels of Prolactin, and it may take several months for serum concentrations to return to non-pregnant levels.
Applications:Suitable for use in Western Blot, Immunohistochemistry and RIA.
Other applications not tested.
Recommended Dilutions:RIA: 1:160,000Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：20ul
Host：rabbit
Source Antibody：sheep
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with 20ul or 100ul sterile ddH2O.
Specificity：Recognizes sheep Prolactin. Species Crossreactivity: deer and ruminants
