Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I.
Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream.
The precursor seems to be activated while it is being transported along the axon to the posterior pituitary.
This hormone contracts smooth muscle during parturition and lactation.
It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behavior, as well as in the regulation of water excretion and cardiovascular functions.
Applications:Suitable for use in RIA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:RIA: 1:80,000Immunohistochemistry (Paraffin): 1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：20ul
Host：rabbit
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with sterile ddH2O.
Specificity：Recognizes Oxytocin. Does not crossreact with Lys-/Arg-vasopressin, neurophysin or pituitary hormones (e.g. prolactin). Species Crossreactivity: human and bovine
Isotype：IgG
Calc Applications Abbrev：IHC RIA WB
Calc Crossreactivity：Bo Hu
Immunogen：Synthetic Oxytocin, conjugated to bovine thyroglobulin
