Human brain natriuretic peptide (BNP) is a secreted protein which is a member of the natriuretic peptide family.
BNP is a cardiac hormone, which is synthesized as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation.
BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system.
A high concentration of BNP in the bloodstream is indicative of heart failure.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:ELISA: capture antibody Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：goat
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with 20ul or 100ul sterile ddH2O.
Specificity：Recognizes synthetic human pro-Brain Natriuretic Peptide (aa32-57). Does not crossreact with human pro-BNP (aa8-29).
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa32-57, QVEQTSLEPLQESPRPTGVWKSREVA of human pro-BNP.
