Human brain natriuretic peptide (BNP) is a secreted protein which is a member of the natriuretic peptide family.
BNP is a cardiac hormone, which is synthesized as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation.
BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system.
A high concentration of BNP in the bloodstream is indicative of heart failure.
Applications:Suitable for use in RIA.
Other applications not tested.
Recommended Dilution:RIA: 1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at 4°C for short-term only.
Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：20ul
Host：rabbit
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder in PBS, pH 7.2. Reconstitute in ddH2O.
Specificity：Recognizes synthetic human BNP (aa 1-10)
Isotype：IgG
Calc Applications Abbrev：RIA
Calc Crossreactivity：Hu
Immunogen：Synthetic human BNP (aa 1-10) polylysinee conjugated (SPKMVQGSGC(G))
