84-1119-97 Collagen Type V (Collagen-V, Alpha 1 Type V Collagen, Collagen alpha-1(V) Chain, Collagen Type V alpha 1, Col5A1, Alpha 2 Type V Collagen, Collagen alpha-2(V) Chain, Collagen Type V alpha 2, Collagen V alpha 2 Polypeptide, Col5A2, Collagen alpha-3(V) Chain, Collagen Type V alpha 3, Col5A3, AB Collagen, MGC105115, Pro-alpha-1 Type V Collagen, Pro alpha 3(V) Collagen, Type V Preprocollagen alpha ... C7510-56K
84-1119-97 Collagen Type V (Collagen-V, Alpha 1 Type V Collagen, Collagen alpha-1(V) Chain, Collagen Type V alpha 1, Col5A1, Alpha 2 Type V Collagen, Collagen alpha-2(V) Chain, Collagen Type V alpha 2, Collagen V alpha 2 Polypeptide, Col5A2, Collagen alpha-3(V) Chain, Collagen Type V alpha 3, Col5A3, AB Collagen, MGC105115, Pro-alpha-1 Type V Collagen, Pro alpha 3(V) Collagen, Type V Preprocollagen alpha ... C7510-56K
Type V collagen is a member of group I collagen (fibrillar forming collagen).
It is a minor connective tissue component of nearly ubiquitous distribution.
Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin.
This gene encodes an alpha chain for one of the low abundance fibrillar collagens.
Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains.
Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen.
This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations.
Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II.
Applications:Suitable for use in ELISA, Western Blot, Immunocytochemistry and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by affinity chromatography
Form:Supplied as a liquid in borate buffered saline. No preservative added.
Specificity:Recognizes conformational determinants on human type V collagen as demonstrated by ELISA. May react with type V collagen from other species. Exhibits < 10% crossreactivity with collagen type I, II, III, IV and VI. Has not been tested for reactivity with other ECM proteins (e.g., laminin, fibronectin).
Isotype:IgG
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Hu
Immunogen:Human type V collagen
Shelf Life:1year
EU Commodity Code:30021010
商品名:Collagen Type V (Collagen-V, Alpha 1 Type V Collagen, Collagen alpha-1(V) Chain, Collagen Type V alpha 1, Col5A1, Alpha 2 Type V Collagen, Collagen alpha-2(V) Chain, Collagen Type V alpha 2, Collagen V alpha 2 Polypeptide, Col5A2, Collagen alpha-3(V) Chain, Collagen Type V alpha 3, Col5A3, AB Collagen, MGC105115, Pro-alpha-1 Type V Collagen, Pro alpha 3(V) Collagen, Type V Preprocollagen alpha 2 Chain) 200ug