TLRs play an important role in the recognition of invading microbial pathogens during innate immunity, acting through adaptor molecules such as MyD88 and TRAF6.
TLR6 acts via a cytokine signaling pathway to induce the activation of NF-kappaB, through the formation of dimers with TLR2 (CD282) which coordinate macrophage activation by Gram-positive bacteria and zymosan.
Studies have also revealed the involvement of TLR6/TLR2 dimers in apoptotic responses, through recognition of mycoplasmal lipoproteins.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.5-1ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography from whole serum.
Form：Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity：Recognizes human TLR6.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：A synthetic peptide corresponding to a 13aa sequence located near the center of human TLR6.
